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Ozempic and Wegovy semiglutide drugs apparently reduce the craving for alcohol

rrrr

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A study by a group at UNC has concluded the semiglutide drugs approved for treatment of obesity by reducing the desire to eat may have the same effect on those that drink excessive amounts of alcohol. While the study was brief in duration and used just 48 subjects, there is hope that establishment of a larger group lasting an extended amount of time will prove that the benefits observed in the initial study will be successfully repeated.

I know that @H20 Toie was able to greatly reduce his food and alcohol intake while undergoing a semiglutide drug regimen.


 
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wallnutz

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I have seen it first hand with my brother. Started a generic Ozempic to lose weight and after a couple of months he is not drinking at all. Before he drank every day and was in failing health due to it. Funny thing is he didn't realize that he was cutting down because it was so slow to start happening. But then again most alcoholics don't know that they are alcoholics.
 

pkrrvr619

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That is a neat side effect. Tough to lose weight when slamming down booze calories so win/win
 

poncho

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Friend of mine is taking one of those, down 40 pounds so far. Works a schedule like mine months on and months off, last time home he said he found himself drinking less, his wife is a self-described dog mom (13), and they would normally start drinking wine in the afternoon and he said he now goes several days without drinking at all.
 

pkrrvr619

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Ive been on a year long weight loss journey working out, logging calories, and eating clean. down 45 pounds of far.

it has been tough as hell at times but has taught me a lot of discipline.

a lot of people see so much success with these weight loss drugs that it is easy to become a hater and think "that is cheating".

But everyone is on their own journey and if using these drugs helps I say go for it as being obese is so bad for one's health.

I think the biggest issue with these types of drugs is that if you're not modifying the behaviors that got you fat to begin with, when you wean off of them it will most of the weight will come back on.

so learning to eat clean, work out, and track calories does become part of the equation as well as weight loss and fitness really is a lifestyle change.
 

H20 Toie

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I have seen it first hand with my brother. Started a generic Ozempic to lose weight and after a couple of months he is not drinking at all. Before he drank every day and was in failing health due to it. Funny thing is he didn't realize that he was cutting down because it was so slow to start happening. But then again most alcoholics don't know that they are alcoholics.
Its so easy to tell, alcoholics go to meetings,
So i'm 10 months into this and down 105 pounds, all my blood test have greatly improved, blood pressure is perfect, so for me it was a awesome choice, zero side effects, size 48 pants to 36-38 now, even bought a shirt that was an xl the other day when 3x's were getting tight before.
As far as drinking i might have 5 to 7 beers in a week, ( compared to that for Lunch a year ago) so even thou it feels like i'm not drinking much i looked it up and 5 to 7 is weekly average, guess i was above average :)
It's weird in that i still like a cold one but i don't ever feel like i need a drink. and having "A" beer at dinner is perfect, Debbie is an awesome cook so when we eat at home i drink water plus without even thinking about it since i'm not eating as much i normally order healthier food. lots of protein
 

OC Daytona

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Ive been on a year long weight loss journey working out, logging calories, and eating clean. down 45 pounds of far.

it has been tough as hell at times but has taught me a lot of discipline.

a lot of people see so much success with these weight loss drugs that it is easy to become a hater and think "that is cheating".

But everyone is on their own journey and if using these drugs helps I say go for it as being obese is so bad for one's health.

I think the biggest issue with these types of drugs is that if you're not modifying the behaviors that got you fat to begin with, when you wean off of them it will most of the weight will come back on.

so learning to eat clean, work out, and track calories does become part of the equation as well as weight loss and fitness really is a lifestyle change.

What works best is when you combine the GLP/GIP's with exercise, better eating and less alcohol. Part of the way the GLP's work is by stabilizing your blood sugar levels. Most ppl regain the weight when they get off of them, because they are no longer controlling their blood sugar levels. That causes insulin spikes and usually weight gain. I'm down over 35 pounds and just on a maintenance dose these days. I usually don't even eat half of my meal even at my favorite restaurants, so I get 2 decent meals when I go out instead of just 1 😁.

I also take chromium picolinate, berberine and cinnamon to help with the blood sugar levels, but none of them work as well for me as Tirzepatide.
 

DarkHorseRacing

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Great, let me sign my brother up for the next study. He'd be a candidate for trialing that, though with him they'd need to hold him down to inject him. He won't admit to it otherwise.
 

OC Daytona

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A study by a group at UNC has concluded the semiglutide drugs approved for treatment of obesity by reducing the desire to eat may have the same effect on those that drink excessive amounts of alcohol. While the study was brief in duration and used just 48 subjects, there is hope that establishment of a larger group lasting an extended amount of time will prove that the benefits observed in the initial study will be successfully repeated.

I know that @H20 Toie was able to greatly reduce his food and alcohol intake while undergoing a semiglutide drug regimen.



I'm a partner in a pharmacy that sells all the GLP1's. In my experience, the one you want is Tirzepatide (Mounjaro or Zepbound by Eli Lilly).
It has 2 G factors...GLP1 and GIP. Wegovy/Ozempic are older and are only GLP. In the clinical trials, ppl on Tirzepatide lost almost double the weight as ppl on Semaglutide and had way less nausea. We only prescribe the Semaglutide for folks that Tirzepatide doesn't work on them. Pricing is the same, but more insurance plans cover for Semaglutide.


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Justfishing

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Ive been on a year long weight loss journey working out, logging calories, and eating clean. down 45 pounds of far.

it has been tough as hell at times but has taught me a lot of discipline.

a lot of people see so much success with these weight loss drugs that it is easy to become a hater and think "that is cheating".

But everyone is on their own journey and if using these drugs helps I say go for it as being obese is so bad for one's health.

I think the biggest issue with these types of drugs is that if you're not modifying the behaviors that got you fat to begin with, when you wean off of them it will most of the weight will come back on.

so learning to eat clean, work out, and track calories does become part of the equation as well as weight loss and fitness really is a lifestyle change.
What do you consider eating clean.
 

spark2678

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Down 65lbs in 6 months on Tirzepatide (Mounjaro). Drink a few on the weekend but my alcohol consumption is drastically down. No desire for it. The stuff is not magic, it curbs appetite a lot but I still eat very healthy, drink more water and have a high dose of protein. I have a friend's wife that lost a lot of weight as well (he's on the boards), I was convinced.

Goal is to be 90lbs down on my 1 year anniversary in August. Then take a maintainer dose for who knows how long. I'm 47, I probably haven't weighed what I am for 15 years and another 25lbs will put me at a weight in my early to mid 20's. Sleep better, joints don't hurt, blood pressure great, mood better, focus better, etc etc.

Nausea and stomach cramps were my major side effects and they weren't even that bad, only for the first 1.5 months and when you dose up. Constipation is also an issue but not terrible.
 
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Big B Hova

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Ive been on a year long weight loss journey working out, logging calories, and eating clean. down 45 pounds of far.

it has been tough as hell at times but has taught me a lot of discipline.

a lot of people see so much success with these weight loss drugs that it is easy to become a hater and think "that is cheating".

But everyone is on their own journey and if using these drugs helps I say go for it as being obese is so bad for one's health.

I think the biggest issue with these types of drugs is that if you're not modifying the behaviors that got you fat to begin with, when you wean off of them it will most of the weight will come back on.

so learning to eat clean, work out, and track calories does become part of the equation as well as weight loss and fitness really is a lifestyle change.
I'm also on a year (well 14 month now) weight loss journey. My wife was dropping weight so I felt guilty...First half of last year was cutting out some junk food and adding some protein shakes into the mix. Over summer it was eating better at home / more whole foods and less processed crap.

I joined kaiser healthy weight classes for tips which wasn't really helpful in my case. I had dropped like 20 lbs in 6 months, but not really exercising or going crazy with a diet.

Started really dieting and watching the portions, as well as started different medical assisted weight loss medications. (First was metformin for a month, didn't do anything except give me crazy nightmares and vivid dreams) then my doctor prescribed Qysmia.

This medicine, combined with my lifestyle changes I was dropping weight. More weight I dropped the more I wanted to exercise and do better.

Fast forward to today... I'm down 68.5 lbs, eating super healthy, bought a bowflex, tracking my steps and exercise with a smart watch and still making progress. Drilling holes in yore belt gives you motivation thats for sure.

Long story short, I really haven't been drinking all that much. I did a few weekends ago and it ruined my Sunday the next morning lol.

Clocked in at 256.5 lbs this morning, less then I weighed high school......

Screenshot_20250218_125520_Samsung Health.jpg
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Tamalewagon

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I'm a partner in a pharmacy that sells all the GLP1's. In my experience, the one you want is Tirzepatide (Mounjaro or Zepbound by Eli Lilly).
It has 2 G factors...GLP1 and GIP. Wegovy/Ozempic are older and are only GLP. In the clinical trials, ppl on Tirzepatide lost almost double the weight as ppl on Semaglutide and had way less nausea. We only prescribe the Semaglutide for folks that Tirzepatide doesn't work on them. Pricing is the same, but more insurance plans cover for Semaglutide.


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What are the long term effects though?
 

pkrrvr619

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I'm also on a year (well 14 month now) weight loss journey. My wife was dropping weight so I felt guilty...m First half of last year was cutting out some junk food and adding some protein shakes into the mix. Over summer it was eating better at home / more whole foods and less processed crap.

I joined kaiser healthy weight classes for tips which wasn't really helpful in my case. I had dropped like 20 lbs in 6 months, but not really exercising or going crazy with a diet.

Started really dieting and watching the portions, as well as started different medical assisted weight loss medications. (First was metformin for a month, didn't do anything except give me crazy nightmares and vivid dreams) then my doctor prescribed Qysmia.

This medicine, combined with my lifestyle changes I was dropping weight. More weight I dropped the more I wanted to exercise and do better.

Fast forward to today... I'm down 68.5 lbs, eating super healthy, bought a bowflex, tracking my steps and exercise with a smart watch and still making progress. Drilling holes in yore belt gives you motivation thats for sure.

Long story short, I really haven't been drinking all that much. I did a few weekends ago and it ruined my Sunday the next morning lol.

Clocked in at 256.5 lbs this morning, less then I weight in high school......

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Fuck yeah man outstanding!
 

pkrrvr619

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What do you consider eating clean.
Single ingredient foods for the most part. If it comes in a box or package don’t eat it. This usually has less calories as it’s less processed.

Example of what I eat in a day:

3 egg scramble with two handfuls of diced onion and bell peppers and ham. This is like 350 calories and is a shit ton of food.

Lunch is meal prepped ground turkey and a vegetable or “sandwiches” which is tuna salad on romaine lettuce. Coke Zero. 3-400 calories.

Dinner. Lean protein (tri tip, chicken, fish, ground 93 lean beef) and a vegetable or salad. 500 calories ish.

Desert is an atkins protein bar which is like a healthier baby Ruth bar.

That’s about 1600 cals which if anyone ate that they would lose weight.

But the only processed stuff would be the Coke Zero and the atkins bar and mayo for lunch.

Eating Whole Foods allows for more filling options at less calories.

When you start tracking calories it’s eye opening how fast they add up. One drive through meal can be a daily allotment of food.

Lose it app is killer for tracking purposes.
 

CLCookie

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question, for you people using it for weight loss, what is your dosage?

I take Ozempic for Diabetes, but only .5 dosage once a week. I certainly see less craving in alcohol and food, but not a lot. What I have seen is it is changing my habits, my dinner time food is much smaller portion and when I eat fatty foods, it messes up my stomach. It is forcing me to eat cleaner.
 

OC Daytona

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Well, for most folks, the long term side effect is you're no longer a diabetic fat fuck with sleep apnea. Clinical trials show a 38% reduction in strokes and heart attacks and a 94% chance you will not be a type2 diabetic. I'll take those odds. My sleep apnea went away as well.

They have only been out a few years, so no 10 year data available yet. They are also noticing ppl on GLP1 have less brain inflammation so they think it will also reduce dementia. All of the doctors I work with are either on it themselves or highly recommend it. Who knows....but I'll bet that not being a diabetic with high blood pressure and sleep apnea is better for your heart and your joints than being 30-50 pounds overweight for the rest of your life.
 

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So are the drugs forever or just temporary? How long is too long or how much is too much? Test and hgh are good too but you can also over do it. Same with insulin. All this stuff is very interesting to me.
 

OC Daytona

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So are the drugs forever or just temporary? How long is too long or how much is too much? Test and hgh are good too but you can also over do it. Same with insulin. All this stuff is very interesting to me.

You know drug companies. They don't cure anything anymore, they only supply treatments. Everybody is a little different due to many factors how long they stay on it, but most ppl that can afford it, don't go off for very long. Once they gain 5 pounds they are back on it. The best way is once you hit your target weight, to go on a maintenance dose approximately half of what you maxed out at to get to your target weight. If you got up to 10mg/week (Mounjaro/Zepbound)....reduce your dose to 5 mg for a few months before you get completely off. If you go off cold turkey, you will almost certainly gain much if not all of the weight back.

Not sure if you are on HGH, but if you are, you might want to take a look at Semorelin. Semorelin is basically HGH with the bad side effects removed. It's been around 25 years and much safer than HGH or Tesmorelin. I have taken both on/off for years. With the Semorelin, you get the things you liked about HGH (strength and some fat burning) but you don't get the hand/finger numbness that I always got after being on HGH for a few months. My .02

Test is good, just make sure to get blood tested for high estrogen and thicker blood due to red blood cell count increasing. If the blood gets too thick, you open yourself up to strokes and heart attacks.
 

jetboatperformance

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I'm 73 hyperactive, with high blood pressure (controlled) and overweight I'd like to live a long healthy life but I'm mature enough to know I wont live forever so what "long term side effects" I might be concerned about are far outweighed by my current state of health for an Old Man 🤣
 

BHC Vic

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You know drug companies. They don't cure anything anymore, they only supply treatments. Everybody is a little different due to many factors how long they stay on it, but most ppl that can afford it, don't go off for very long. Once they gain 5 pounds they are back on it. The best way is once you hit your target weight, to go on a maintenance dose approximately half of what you maxed out at to get to your target weight. If you got up to 10mg/week (Mounjaro/Zepbound)....reduce your dose to 5 mg for a few months before you get completely off. If you go off cold turkey, you will almost certainly gain much if not all of the weight back.

Not sure if you are on HGH, but if you are, you might want to take a look at Semorelin. Semorelin is basically HGH with the bad side effects removed. It's been around 25 years and much safer than HGH or Tesmorelin. I have taken both on/off for years. With the Semorelin, you get the things you liked about HGH (strength and some fat burning) but you don't get the hand/finger numbness that I always got after being on HGH for a few months. My .02

Test is good, just make sure to get blood tested for high estrogen and thicker blood due to red blood cell count increasing. If the blood gets too thick, you open yourself up to strokes and heart attacks.
I’m not on hgh but have really been looking into that and trt levels of test. I just got blood drawn Friday to see where I’m at. Real hgh at the doses I’m looking at could get expensive quick. Thanks for the good info I still have more homework to do
 

OC Daytona

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I’m not on hgh but have really been looking into that and trt levels of test. I just got blood drawn Friday to see where I’m at. Real hgh at the doses I’m looking at could get expensive quick. Thanks for the good info I still have more homework to do
Vic.....PM me with your # if you want to chat about it.....I can give you good info on both
 

H20 Toie

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question, for you people using it for weight loss, what is your dosage?

I take Ozempic for Diabetes, but only .5 dosage once a week. I certainly see less craving in alcohol and food, but not a lot. What I have seen is it is changing my habits, my dinner time food is much smaller portion and when I eat fatty foods, it messes up my stomach. It is forcing me to eat cleaner.
I use mounjaro and she started me at .5 then bumped up to .75, i eat waaaay less, even in key west eating a ton of crap food and lots of different drinks it didn't effect my stomach at all, guess i'm lucky
 

OC Daytona

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I use mounjaro and she started me at .5 then bumped up to .75, i eat waaaay less, even in key west eating a ton of crap food and lots of different drinks it didn't effect my stomach at all, guess i'm lucky

So do you load your own syringe or are they sending you preloaded syringes with 0.5 and 0.75 full on a 1.0 ml syringe?
The actual dose will be in milligrams (mg). I'm guessing the .5 is 5mg and the .75 is 7.5mg, the actual dose depends on how many mg/ml the concentration of what you are loading is. We mostly use 10mg/ml., so 0.5 ml in the syringe is 5mg and a full syringe is 10mg.

they are also now making 15mg/ml......so if that's what you are getting....0.5 is actually 7.5mg not 5mg
usually a big difference in price as well
 

H20 Toie

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So do you load your own syringe or are they sending you preloaded syringes with 0.5 and 0.75 full on a 1.0 ml syringe?
The actual dose will be in milligrams (mg). I'm guessing the .5 is 5mg and the .75 is 7.5mg, the actual dose depends on how many mg/ml the concentration of what you are loading is. We mostly use 10mg/ml., so 0.5 ml in the syringe is 5mg and a full syringe is 10mg.

they are also now making 15mg/ml......so if that's what you are getting....0.5 is actually 7.5mg not 5mg
usually a big difference in price as well
it comes in a pen, i take the cap off put it against my fat,. push the button, wait to hear the click, it's done, can't even feel it, it doesn't even leave a mark
You are right it’s 7.5


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jetboatperformance

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My "Good Nurse" Rhonda loads the syringes and I do the actual injection , the needle stick doesn't hurt But kinda itches at the injection site some times. I've had zero "bad" side effects , FWIW My mostly bald dome had minor psoriasis and keratosis spots for years , It has completely disappeared (another know good side effect BTW)
 

Willie B

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… weight loss and health is in this book👍
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gqchris

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Test is good, just make sure to get blood tested for high estrogen and thicker blood due to red blood cell count increasing. If the blood gets too thick, you open yourself up to strokes and heart attacks.
100% this. I loved being on TRT, Changes my mood and just makes me feel better overall. I have tried it 4 times over 10 years, each time my RBC levels get too high and I cant get them down, even with biweekly blood draws! Sucks, it seems that some people just have a tendency towards it. I had to stop every time, but man, I miss it!
 

pkrrvr619

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100% this. I loved being on TRT, Changes my mood and just makes me feel better overall. I have tried it 4 times over 10 years, each time my RBC levels get too high and I cant get them down, even with biweekly blood draws! Sucks, it seems that some people just have a tendency towards it. I had to stop every time, but man, I miss it!
what were your levels when you got on it?
 

OC Daytona

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Chris, I'm guessing you were on the newer T that is 200mg/ml Did you try just doing half a ml instead of a full/ml. That's still 100mg a week, which will give you a boost.
The other thing you could take is Semorelin. Most ppl that are on that like it as much as T. It's around $150/month for good Semorelin.

A lot of folks with high RBC will lower their T dose to half. You still get LOTS of the benefits, but your RBC doesn't go thru the roof.
RBC results of 16-17.5 are OK, you just don't want to get over 18 for long......19 and above is like running your boat on the rev limiter all day :eek: :oops:;)

Call me if you have any questions. 949-632-2352

Tom
 

gqchris

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Chris, I'm guessing you were on the newer T that is 200mg/ml Did you try just doing half a ml instead of a full/ml. That's still 100mg a week, which will give you a boost.
The other thing you could take is Semorelin. Most ppl that are on that like it as much as T. It's around $150/month for good Semorelin.

A lot of folks with high RBC will lower their T dose to half. You still get LOTS of the benefits, but your RBC doesn't go thru the roof.
RBC results of 16-17.5 are OK, you just don't want to get over 18 for long......19 and above is like running your boat on the rev limiter all day :eek: :oops:;)

Call me if you have any questions. 949-632-2352

Tom
Thanks Tom, Yup I was running 18 on the Hemoglobin, was to high for my comfort level! My normal is 15.2

I forget my dose, was using TRT Nation. I just got spooked when my blood shot up again and my PCP was getting concerned also!
 

Justfishing

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Single ingredient foods for the most part. If it comes in a box or package don’t eat it. This usually has less calories as it’s less processed.

Example of what I eat in a day:

3 egg scramble with two handfuls of diced onion and bell peppers and ham. This is like 350 calories and is a shit ton of food.

Lunch is meal prepped ground turkey and a vegetable or “sandwiches” which is tuna salad on romaine lettuce. Coke Zero. 3-400 calories.

Dinner. Lean protein (tri tip, chicken, fish, ground 93 lean beef) and a vegetable or salad. 500 calories ish.

Desert is an atkins protein bar which is like a healthier baby Ruth bar.

That’s about 1600 cals which if anyone ate that they would lose weight.

But the only processed stuff would be the Coke Zero and the atkins bar and mayo for lunch.

Eating Whole Foods allows for more filling options at less calories.

When you start tracking calories it’s eye opening how fast they add up. One drive through meal can be a daily allotment of food.

Lose it app is killer for tracking purposes.
I dont track calories. I track my protien. I eat about 1 g per lb of weight. I dont eat lean meats so hamburger is 80/20. Skin on dark meat chickem, bacon, eggs , half and half instead of milk, butter. I use tallow or lard. I have no problem staying lean.

Avoid rice, flour, potatoes, oils, sugar. This eliminates processed foods.

My blood tests came back good. I have a low a1c. Blood pressure was good.
 

pkrrvr619

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I dont track calories. I track my protien. I eat about 1 g per lb of weight. I dont eat lean meats so hamburger is 80/20. Skin on dark meat chickem, bacon, eggs , half and half instead of milk, butter. I use tallow or lard. I have no problem staying lean.

Avoid rice, flour, potatoes, oils, sugar. This eliminates processed foods.

My blood tests came back good. I have a low a1c. Blood pressure was good.
Yep that’s a solid plan for maintenance. For us fatties tracking Cal’s is paramount to drop lbs.
 
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