My trailer is 12” taller than standard enclosed trailers so it has a little more wind resistance. To clarify I can pull it at 75 but its in 7/8 gear and gas mileage is cut nearly in half. My company truck has the 2.7 and has a lot of giddy-up when empty, but it’s a 2WD extended cab so somewhat lighter than my 4WD crew cab. They are ‘16 and ‘17 respectively. Love the gas mileage though if I’m not towing.We tow a steel horse trailer with 3 horses in mine from time to time and it handles it no issues. And it is only the 2.7L.
I prefer to use my F450, but if I am at race with the dirtbike hauler with my son, the wife and the F150 get horse duty if we have both things going the same weekend.